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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BLM All Species: 13.03
Human Site: S499 Identified Species: 22.05
UniProt: P54132 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54132 NP_000048.1 1417 159000 S499 F N T H L Q K S F V S S N W A
Chimpanzee Pan troglodytes XP_510594 1417 158822 S499 F N T H L Q K S F V S S N W A
Rhesus Macaque Macaca mulatta XP_001097543 1416 158885 S498 F N T P L Q K S F V S S N W A
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O88700 1416 158347 S504 L N S H L Q K S F V S S N W A
Rat Rattus norvegicus Q6AYJ1 621 69624
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515695 791 89186
Chicken Gallus gallus Q9I920 1142 126164 C280 A G N P A L G C W D V N D T D
Frog Xenopus laevis Q9DEY9 1364 152305 M469 R A G G D S I M E N S F N F H
Zebra Danio Brachydanio rerio XP_701357 1261 139417 Q399 C G T E L L L Q R A H R K R I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGI8 1487 166060 E577 L D G D L E E E Q L N G P T Q
Honey Bee Apis mellifera XP_396209 961 109321 P99 E N D N L R T P K K C L K T K
Nematode Worm Caenorhab. elegans O18017 988 110641 D126 L V D P P I V D L D E E P P I
Sea Urchin Strong. purpuratus XP_001175892 1394 152920 K503 Q N G A L A S K S L P T R A Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P35187 1447 163819 E520 D L L E D D L E K D A I L D D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 96.1 N.A. N.A. 76.9 21.2 N.A. 46.3 47.9 50.8 41.6 N.A. 27.8 30.9 26.5 31.5
Protein Similarity: 100 99.2 97.7 N.A. N.A. 85.2 30.9 N.A. 50.1 60.7 66.6 54 N.A. 47 47.1 40.2 47.6
P-Site Identity: 100 100 93.3 N.A. N.A. 86.6 0 N.A. 0 0 13.3 13.3 N.A. 6.6 13.3 0 13.3
P-Site Similarity: 100 100 93.3 N.A. N.A. 93.3 0 N.A. 0 20 20 13.3 N.A. 40 26.6 0 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 8 8 8 0 0 0 8 8 0 0 8 29 % A
% Cys: 8 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % C
% Asp: 8 8 15 8 15 8 0 8 0 22 0 0 8 8 15 % D
% Glu: 8 0 0 15 0 8 8 15 8 0 8 8 0 0 0 % E
% Phe: 22 0 0 0 0 0 0 0 29 0 0 8 0 8 0 % F
% Gly: 0 15 22 8 0 0 8 0 0 0 0 8 0 0 0 % G
% His: 0 0 0 22 0 0 0 0 0 0 8 0 0 0 8 % H
% Ile: 0 0 0 0 0 8 8 0 0 0 0 8 0 0 15 % I
% Lys: 0 0 0 0 0 0 29 8 15 8 0 0 15 0 8 % K
% Leu: 22 8 8 0 58 15 15 0 8 15 0 8 8 0 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 43 8 8 0 0 0 0 0 8 8 8 36 0 0 % N
% Pro: 0 0 0 22 8 0 0 8 0 0 8 0 15 8 0 % P
% Gln: 8 0 0 0 0 29 0 8 8 0 0 0 0 0 15 % Q
% Arg: 8 0 0 0 0 8 0 0 8 0 0 8 8 8 0 % R
% Ser: 0 0 8 0 0 8 8 29 8 0 36 29 0 0 0 % S
% Thr: 0 0 29 0 0 0 8 0 0 0 0 8 0 22 0 % T
% Val: 0 8 0 0 0 0 8 0 0 29 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 29 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _